2006
• Arakaki T, Le Trong I, Phizicky E, Quartley E, DeTitta G, Luft J, Lauricella A, Anderson L, Kalyuzhniy O, Worthey E, Myler PJ, Kim D, Baker D, Hol WG, Merritt EA. Structure of Lmaj006129AAA, a hypothetical protein from Leishmania major. Acta Crystallograph Sect F Struct Biol Cryst Commun. 2006 Mar 1;62(Pt 3):175-9.
• Bosch J, Robien MA, Mehlin C, Boni E, Riechers A, Buckner FS, Van Voorhis WC, Myler PJ, Worthey EA, DeTitta G, Luft JR, Lauricella A, Gulde S, Anderson LA, Kalyuzhniy O, Neely HM, Ross J, Earnest TN, Soltis M, Schoenfeld L, Zucker F, Merritt EA, Fan E, Verlinde CL, Hol WG. Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase. J Med Chem. 2006 Oct 5;49(20):5939-46.
• Caruthers J, Bosch J, Buckner F, Van Voorhis W, Myler P, Worthey E, Mehlin C, Boni E, DeTitta G, Luft J, Lauricella A, Kalyuzhniy O, Anderson L, Zucker F, Soltis M, Hol WG. Structure of a ribulose 5-phosphate 3-epimerase from Plasmodium falciparum. Proteins. 2006 Feb 1;62(2):338-42.
• Cody V, Schwalbe CH. Structural characteristics of antifolate dihydrofolate reductase enzyme interactions. Crystallography Reviews. 2006 Oct;12(4):301-33.
• Cody V, Pace J, Chisum K, Rosowsky A. New insights into DHFR interactions: analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions. Proteins. 2006 Dec1;65(4):959-69.
• Drake EJ, Nicolai DA, Gulick AM. Structure of the EntB multidomain nonribosomal peptide synthetase and functional analysis of its interaction with the EntE adenylation domain. Chem Biol. 2006 Apr;13(4):409-19.
• Ericsson UB, Hallberg BM, DeTitta GT, Dekker N, Nordlund P. Thermofluor-based high-throughput stability optimization of proteins for structural studies. Anal Biochem. 2006 Oct 15;357(2):289-98.
• He H, Zatorska D, Kim J, Aguirre J, Llauger L, She Y, Wu N, Immormino RM, Gewirth DT, Chiosis G. Identification of potent water soluble purine-scaffold inhibitors of the heat shock protein 90. J Med Chem. 2006 Jan 12;49(1):381-90.
• Holmes MA, Buckner FS, Van Voorhis WC, Mehlin C, Boni E, Earnest TN, DeTitta G, Luft J, Lauricella A, Anderson L, Kalyuzhniy O, Zucker F, Schoenfeld LW, Hol WG, Merritt EA. Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum. Acta Crystallograph Sect F Struct Biol Cryst Commun. 2006 Mar 1;62(Pt 3):180-5.
• Holmes MA, Buckner FS, Van Voorhis WC, Verlinde CL, Mehlin C, Boni E, DeTitta G, Luft J, Lauricella A, Anderson L, Kalyuzhniy O, Zucker F, Schoenfeld LW, Earnest TN, Hol WG, Merritt EA. Structure of ribose 5-phosphate isomerase from Plasmodium falciparum. Acta Crystallograph Sect F Struct Biol Cryst Commun. 2006 May 1;62(Pt 5):427-31.
• Immormino RM, Kang Y, Chiosis G, Gewirth DT. Structural and quantum chemical studies of 8-aryl-sulfanyl adenine class Hsp90 inhibitors. J Med Chem. 2006 Aug 10;49(16):4953-60.
• Meilleur F, Snell EH, van der Woerd MJ, Judge RA, Myles DA. A quasi-Laue neutron crystallographic study of D: -xylose isomerase. Eur Biophys J. 2006 May 4.
• Pletnev
VZ, Thomas JL, Rhaney FL, Holt LS, Scaccia LA, Umland TC and Duax WL. Rational
Proteomics V: Structure-based mutagenesis has revealed key residues responsible
for substrate recognition and catalysis by the dehydrogenase and isomerase
activities in human 3beta-hydroxysteroid dehydrogenase/isomerase type
1.
J. Steroid.Biochem Mol Biol. 2006 Sep; 101(1): 50-60.
• Robien MA, Bosch J, Buckner FS, Van Voorhis WC, Worthey EA, Myler P, Mehlin C, Boni EE, Kalyuzhniy O, Anderson L, Lauricella A, Gulde S, Luft JR, DeTitta G, Caruthers JM, Hodgson KO, Soltis M, Zucker F, Verlinde CL, Merritt EA, Schoenfeld LW, Hol WG. Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum at 2.25 A resolution reveals intriguing extra electron density in the active site. Proteins. 2006 Mar 15;62(3):570-7.
• Schwalbe CH, Cody V. Structural characteristics of small-molecule antifolate compounds. Crystallography Reviews. 2006 Oct;12(4):267-300.
• Snell
EH, van der Woerd MJ, Damon M, Judge RA, Myles DA, Meilleur F. Optimizing
crystal volume for neutron diffraction: D: -xylose isomerase. Eur
Biophys J. 2006 May 25.
• Sundlov JA, Garringer JA, Carney JM, Reger AS, Drake EJ, Duax
WL, Gulick AM. Determination
of the crystal structure of EntA, a 2,3-dihydro-2,3-dihydroxybenzoic acid dehydrogenase
from Escherichia coli. Acta Crystallogr D Biol Crystallogr. 2006
Jul;62(Pt 7):734-40.
• Williams AH, Immormino RM, Gewirth DT, Raetz CR. Structure of UDP-N-acetylglucosamine acyltransferase with a bound antibacterial pentadecapeptide. Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):10877-82.
• Xu H, Hauptman HA. Recent advances in direct phasing methods for heavy-atom substructure determination. Acta Crystallogr D Biol Crystallogr. 2006 Aug;62(Pt 8):897-90