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Table of Contents Includes:

• A Preliminary Time-of-Flight Neutron Diffraction Study of a Site-Specific Mutant (W3Y) of Rubredoxin from Pyrococcus furiosus  Paul Langan, Xinmin Li, and Benno P. Schoenborn  
• Analysis of Neutron Laue Diffraction from Deuterium-Exchanged TRP Repressor  Catherine L. Lawson and Alexander S.  Chin  
• Towards Large Molecule Crystallography at ISIS  Chick C. Wilson
• Hydrogen and Hydration in Protein Structural Chemistry  Nobuo Niimura, Ichiro Tanaka, Toshiyuki Chatake, Kazuo Kurihara, Mitsuru Maeda and Shigeki Arai
• Evolution and Directions in Macromolecular Neutron Science  Benno P. Schoenborn
• Neutron “Small-Angle” Crystallography: Contrast Variation in Single Crystals of Biological Macromolecules  P.A. Timmins
• Design and Expected Performance of a High Resolution Macromolecular Neutron Diffraction (MaNDi) at the Spallation Neutron Source  P. Thiyagarajan, A.J. Schultz, Ch. Rehm, J.P. Hodges, W.T. Lee and A. Mesecar 
• Recent Trends and Advances in Neutron Macromolecular Crystallography  D.A.A. Myles
• Neutron Protein Crystallography; Some Case Studies at Current Capabilities and Beyond  Matthew Blakeley, Jarjis Habash, John. R. Helliwell, Dean Myles and James Raftery