W0376
Structure Analysis of Reaction Intermediates Trapped in
Crystalline Lattice. Yuji Ohashi, Masaki Kawano and Akifumi Takayama,
Department of Chemistry and Materials Science, Tokyo Institute of Technology,
O-okayama, Meguro-ku, Tokyo 152-8551, Japan.
Many organic reactions proceed by multi step processes in
which intermediate molecular species are involved in the conversion from one
molecule to another. Such intermediate molecules, in general, are so unstable
at room temperature that the structure analysis has been considered to be very
difficult. However, the unstable species produced by photo irradiation may be
trapped in the crystalline lattice at low temperatures and the structures can be
analyzed by X-ray technique.
The first example is a triplet carbene. When a single crystal
of 2,2’,4,4’,6,6’-hexachlorodiphenyldiazomethane was
irradiated with 365 nm light from a high-pressure mercury lamp at low
temperatures below 80 K for 2 h, the crystal turned from yellow to red retaining
the single crystal form. The crystal structure after irradiation indicated that
a dinitrogen molecule and the hexachlorodiphenylcarbene were produced in the
crystalline lattice. The salient feature of the carbene structure is the
carbenic angle of the central carbon (142(2)°), which is wider by
about 15° than the corresponding angle of the original diazomethane. The
second example is a nitrene. When the crystal of 2-azidobiphenyl was irradiated
with light (>420 nm) for 5 h, the crystal color changed from colorless to
brown with retention of the single crystal form. The structure after
irradiation revealed that the molecule is changed to a dinitrogen molecule and a
2-biphenylnitrene due to the cleavage of the azido group. These results made
clear the reaction mechanism.